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PDBsum entry 3geb

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protein metals Protein-protein interface(s) links
Hydrolase PDB id
3geb
Jmol
Contents
Protein chain
258 a.a. *
Metals
_MG ×4
Waters ×82
* Residue conservation analysis
PDB id:
3geb
Name: Hydrolase
Title: Crystal structure of edeya2
Structure: Eyes absent homolog 2. Chain: a, b, c, d. Fragment: c-terminal domain. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.40Å     R-factor:   0.171     R-free:   0.218
Authors: S.J.Kim
Key ref: S.J.Kim et al. Structure of edeya2. To be published, .
Date:
25-Feb-09     Release date:   07-Apr-09    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam  
O00167  (EYA2_HUMAN) -  Eyes absent homolog 2
Seq:
Struc:
 
Seq:
Struc:
538 a.a.
258 a.a.*
Key:    Secondary structure
* PDB and UniProt seqs differ at 3 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: E.C.3.1.3.48  - Protein-tyrosine-phosphatase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Protein tyrosine phosphate + H2O = protein tyrosine + phosphate
Protein tyrosine phosphate
+ H(2)O
= protein tyrosine
+ phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     multicellular organismal development   2 terms 
  Biochemical function     protein tyrosine phosphatase activity     1 term