spacer
spacer

PDBsum entry 3fyi

Go to PDB code: 
protein ligands metals Protein-protein interface(s) links
Oxidoreductase PDB id
3fyi
Jmol
Contents
Protein chains
535 a.a. *
256 a.a. *
Ligands
HEA ×4
CYN ×2
DMU ×10
TRD ×12
HTO
Metals
CU1 ×6
_MG ×2
_CA ×2
_CD ×4
Waters ×470
* Residue conservation analysis
PDB id:
3fyi
Name: Oxidoreductase
Title: Catalytic core subunits (i and ii) of cytochromE C oxidase from rhodobacter sphaeroides in the reduced state bound with cyanide
Structure: CytochromE C oxidase subunit 1. Chain: a, c. Synonym: cytochromE C oxidase polypeptide i, cytochrome aa3 subunit 1. Engineered: yes. CytochromE C oxidase subunit 2. Chain: b, d. Synonym: cytochromE C oxidase polypeptide ii, cytochrome aa3 subunit 2, oxidase aa(3) subunit 2.
Source: Rhodobacter sphaeroides. Rhodopseudomonas sphaeroides. Organism_taxid: 1063. Gene: ctad. Expressed in: rhodobacter sphaeroides. Expression_system_taxid: 1063. Gene: ctac, coxii, ctab.
Resolution:
2.20Å     R-factor:   0.195     R-free:   0.219
Authors: L.Qin,D.A.Mills,D.A.Proshlyakov,C.Hiser,S.Ferguson-Miller
Date:
22-Jan-09     Release date:   16-Jun-09    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
P33517  (COX1_RHOSH) -  Cytochrome c oxidase subunit 1
Seq:
Struc:
 
Seq:
Struc:
566 a.a.
535 a.a.
Protein chains
Pfam   ArchSchema ?
Q03736  (COX2_RHOSH) -  Cytochrome c oxidase subunit 2
Seq:
Struc:
303 a.a.
256 a.a.*
Key:    PfamA domain  PfamB domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 4 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: Chains A, B, C, D: E.C.1.9.3.1  - Cytochrome-c oxidase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O
4 × ferrocytochrome c
Bound ligand (Het Group name = HEA)
matches with 50.00% similarity
+ O(2)
+ 4 × H(+)
= 4 × ferricytochrome c
+ 2 × H(2)O
      Cofactor: Cu cation
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     membrane   4 terms 
  Biological process     oxidation-reduction process   8 terms 
  Biochemical function     electron carrier activity     7 terms