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PDBsum entry 3fxp

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protein ligands metals links
Hydrolase PDB id
3fxp
Jmol
Contents
Protein chain
316 a.a. *
Ligands
D38
GLO
Metals
_CA ×4
_ZN
Waters ×150
* Residue conservation analysis
PDB id:
3fxp
Name: Hydrolase
Title: Thermolysin inhibition
Structure: Thermolysin. Chain: a. Fragment: unp residues 233-548. Synonym: thermostable neutral proteinase. Ec: 3.4.24.27
Source: Bacillus thermoproteolyticus. Organism_taxid: 1427
Resolution:
2.05Å     R-factor:   0.189     R-free:   0.265
Authors: L.Englert,A.Heine,G.Klebe
Key ref: L.Englert et al. Thermolysin in complex with triazolic inhibitor. To be published, .
Date:
21-Jan-09     Release date:   09-Feb-10    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P00800  (THER_BACTH) -  Thermolysin
Seq:
Struc:
 
Seq:
Struc:
548 a.a.
316 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.3.4.24.27  - Thermolysin.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Preferential cleavage: Xaa-|-Leu > Xaa-|-Phe.
      Cofactor: Ca(2+); Zn(2+)
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     proteolysis   1 term 
  Biochemical function     metalloendopeptidase activity     1 term