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Protein binding
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PDB id
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3fdt
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Contents |
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* Residue conservation analysis
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PDB id:
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Protein binding
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Title:
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Crystal structure of the complex of human chromobox homolog with h3k9(me)3 peptide
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Structure:
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Chromobox protein homolog 5. Chain: a. Synonym: heterochromatin protein 1 homolog alpha, hp1 alpha p25. Engineered: yes. H3k9(me)3 peptide. Chain: t. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: cbx5, hp1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: unspecified
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Resolution:
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2.00Å
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R-factor:
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0.199
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R-free:
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0.257
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Authors:
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M.F.Amaya,M.Ravichandran,P.Loppnau,I.Kozieradzki,A.M.Edwards C.H.Arrowsmith,J.Weigelt,C.Bountra,A.Bochkarev,J.Min,H.Ouya Structural Genomics Consortium (Sgc)
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Key ref:
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L.Kaustov
et al.
(2011).
Recognition and specificity determinants of the human cbx chromodomains.
J Biol Chem,
286,
521-529.
PubMed id:
DOI:
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Date:
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26-Nov-08
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Release date:
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13-Jan-09
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PROCHECK
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Headers
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References
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P45973
(CBX5_HUMAN) -
Chromobox protein homolog 5
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Seq:
Struc:
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191 a.a.
51 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Gene Ontology (GO) functional annotation
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Cellular component
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nucleus
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2 terms
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Biological process
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chromatin assembly or disassembly
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1 term
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Biochemical function
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chromatin binding
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1 term
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DOI no:
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J Biol Chem
286:521-529
(2011)
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PubMed id:
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Recognition and specificity determinants of the human cbx chromodomains.
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L.Kaustov,
H.Ouyang,
M.Amaya,
A.Lemak,
N.Nady,
S.Duan,
G.A.Wasney,
Z.Li,
M.Vedadi,
M.Schapira,
J.Min,
C.H.Arrowsmith.
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ABSTRACT
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Literature references that cite this PDB file's key reference
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PubMed id
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Reference
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Y.Chang,
J.R.Horton,
M.T.Bedford,
X.Zhang,
and
X.Cheng
(2011).
Structural insights for MPP8 chromodomain interaction with histone H3 lysine 9: potential effect of phosphorylation on methyl-lysine binding.
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J Mol Biol, 408,
807-814.
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PDB code:
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The most recent references are shown first.
Citation data come partly from CiteXplore and partly
from an automated harvesting procedure. Note that this is likely to be
only a partial list as not all journals are covered by
either method. However, we are continually building up the citation data
so more and more references will be included with time.
Where a reference describes a PDB structure, the PDB
code is
shown on the right.
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Links
