PDBsum entry 3f1c

Transferase

PDB id: 3f1c

Contents

Protein chains

229 a.a. *

Waters ×67

* Residue conservation analysis

PDB id:

3f1c

Name:

Transferase

Title:

Crystal structure of 2-c-methyl-d-erythritol 4-phosphate cytidylyltransferase from listeria monocytogenes

Structure:

Putative 2-c-methyl-d-erythritol 4-phosphate cytidylyltransferase 2. Chain: a, b. Synonym: 4-diphosphocytidyl-2c-methyl-d-erythritol synthase 2, mep cytidylyltransferase 2, mct 2. Engineered: yes

Source:

Listeria monocytogenes str. 4b f2365. Organism_taxid: 265669. Gene: ispd2, lmof2365_1100. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

2.30Å R-factor: 0.242 R-free: 0.277

Authors:

Y.Patskovsky,J.Ho,R.Toro,M.Gilmore,S.Miller,C.Groshong,J.M.Sauder, S.K.Burley,New York Sgx Research Center For Structural Genomics (Nysgxrc)

Key ref:

Y.Patskovsky et al. Crystal structure of 2-C-Methyl-D-Erythritol 4-Phosphate cytidylyltransferase from listeria monocytogenes. To be published, .

Date:

27-Oct-08 Release date: 18-Nov-08

Protein chains

Q720Y7  (TARI_LISMF) -  Ribitol-5-phosphate cytidylyltransferase from Listeria monocytogenes serotype 4b (strain F2365)

Seq: 237 a.a.

Struc: 229 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.2.7.7.40 - D-ribitol-5-phosphate cytidylyltransferase.
• Reaction: D-ribitol 5-phosphate + CTP + H⁺ = CDP-L-ribitol + diphosphate

Molecule diagrams generated from .mol files obtained from the KEGG ftp site