PDBsum entry: 3etd

Oxidoreductase

PDB id

3etd

Contents

			Protein chains

					(+ 0 more) 501 a.a. *

			Ligands

					GLU ×6


					NDP ×6


					GTP ×6


					B1T ×6

			Waters ×88

* Residue conservation analysis

PDB id:

3etd

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Name:

Oxidoreductase

Title:

Structure of glutamate dehydrogenase complexed with bithionol

Structure:

Glud1 protein. Chain: a, b, c, d, e, f

Source:

Bos taurus. Bovine,cow. Organism_taxid: 9913. Tissue: liver

Resolution:

2.50Å

R-factor:

0.239

R-free:

0.257

Authors:

M.Li,T.J.Smith

Date:

07-Oct-08

Release date:

09-Jun-09

	Headers

	References

Protein chains

P00366 (DHE3_BOVIN) - Glutamate dehydrogenase 1, mitochondrial

Seq: Struc:

Seq: Struc:					558 a.a. 501 a.a.*

Key:

PfamA domain

Secondary structure

CATH domain

* PDB and UniProt seqs differ at 5 residue positions (black crosses)



		Enzyme reactions

Enzyme class:

E.C.1.4.1.3 - Glutamate dehydrogenase (NAD(P)(+)).

[IntEnz] [ExPASy] [KEGG] [BRENDA]

Reaction:

L-glutamate + H₂O + NAD(P)(+) = 2-oxoglutarate + NH₃ + NAD(P)H

L-glutamate
Bound ligand (Het Group name = GLU)
matches with 90.00% similarity

H(2)O

NAD(P)(+)
Bound ligand (Het Group name = NDP)
corresponds exactly

2-oxoglutarate

NH(3)

NAD(P)H

Molecule diagrams generated from .mol files obtained from the KEGG ftp site



		Gene Ontology (GO) functional annotation

Cellular component	mitochondrion	3 terms
Biological process	metabolic process	4 terms
Biochemical function	catalytic activity	9 terms