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Contents |
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* Residue conservation analysis
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PDB id:
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Splicing
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Title:
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Crystal structure of the rhogef domain of human neuroepithel transforming gene 1 protein
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Structure:
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Neuroepithelial cell-transforming gene 1 protein. Chain: a. Fragment: unp residues 161-373. Synonym: p65 net1 proto-oncogene, rho guanine nucleotide ex factor 8. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: net1, arhgef8. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Resolution:
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2.60Å
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R-factor:
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0.215
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R-free:
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0.250
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Authors:
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L.Nedyalkova,Y.Tong,W.Tempel,F.Mackenzie,C.H.Arrowsmith,A.M. C.Bountra,J.Weigelt,A.Bochkarev,H.Park,Structural Genomics Consortium (Sgc)
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Key ref:
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L.Nedyalkova
et al.
Crystal structure of the rhogef domain of human neuroepithelial cell-Transforming gene 1 protein.
To be published,
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Date:
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26-Sep-08
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Release date:
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07-Oct-08
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PROCHECK
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Headers
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References
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Q7Z628
(ARHG8_HUMAN) -
Neuroepithelial cell-transforming gene 1 protein
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Seq: Struc:
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596 a.a.
187 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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Gene Ontology (GO) functional annotation
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Cellular component
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intracellular
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1 term
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Biological process
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intracellular signal transduction
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2 terms
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Biochemical function
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guanyl-nucleotide exchange factor activity
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2 terms
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