 |

*
Residue conservation analysis
|
|
| PDB id: |
 |
3eo2
|
 |
| Name: |
 |
Splicing
|
 |
| Title: |
 |
Crystal structure of the rhogef domain of human neuroepithelial cell-transforming gene 1 protein
|
 |
 Structure: |
 |
Neuroepithelial cell-transforming gene 1 protein. Chain: a. Fragment: unp residues 161-373. Synonym: p65 net1 proto-oncogene, rho guanine nucleotide exchange factor 8. Engineered: yes
|
 |

Source:
|
 |
Homo sapiens. Human. Organism_taxid: 9606. Gene: net1, arhgef8. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
 |

UniProt:
|
 |
| Seq: |
 |
 |
 |
 |
|
| Struc: |
 |
 |
 |
| Seq: |
 |
 |
 |
 |
|
| Struc: |
 |
 |
 |
| Seq: |
 |
 |
 |
596 a.a. |
|
| Struc: |
187 a.a. |
 |
 |
 |
| Key: |
 |
PfamA domain |
 |
 |
PfamB domain |
 |
 |
 |
Secondary structure |
 |
 |
CATH domain |
 |
|
|
|
 |

Resolution:
|
 |
2.60Å
|
 |

R-factor:
|
 |
0.215
|
 |

R-free:
|
 |
0.250
|
 |

Authors:
|
 |
L.Nedyalkova,Y.Tong,W.Tempel,F.Mackenzie,C.H.Arrowsmith, A.M.Edwards,C.Bountra,J.Weigelt,A.Bochkarev,H.Park, Structural Genomics Consortium (Sgc)
|
 |

Key ref:
|
 |
l.nedyalkova
et al.
crystal structure of the rhogef domain of human neuroepithelial cell-transforming gene 1 protein.
TO BE PUBLISHED,
.
|
 |

Date:
|
 |
26-Sep-08
|
 |

Release date:
|
 |
07-Oct-08
|
 |
|
|
|
 |
Quick_links |
 |
 |
Procheck |
 |
 |
Clefts |
 |
 |
Surface |
 |
|
|