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Splicing PDB-id
3eo2
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Protein chain
187 a.a. *
Ligands
UNX

* Residue conservation analysis
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PDB id: 3eo2
Name: Splicing
Title: Crystal structure of the rhogef domain of human neuroepithelial cell-transforming gene 1 protein

Structure:
Neuroepithelial cell-transforming gene 1 protein. Chain: a. Fragment: unp residues 161-373. Synonym: p65 net1 proto-oncogene, rho guanine nucleotide exchange factor 8. Engineered: yes

Source:
Homo sapiens. Human. Organism_taxid: 9606. Gene: net1, arhgef8. Expressed in: escherichia coli. Expression_system_taxid: 562.

UniProt:
Q7Z628 (ARHG8_HUMAN) Pfam   ArchSchema ?
Seq:
Struc:
Seq:
Struc:
Seq: 596 a.a.
Struc: 187 a.a.
Key:    PfamA domain  PfamB domain
 Secondary structure  CATH domain

Resolution:
2.60Å

R-factor:
0.215

R-free:
0.250

Authors:
L.Nedyalkova,Y.Tong,W.Tempel,F.Mackenzie,C.H.Arrowsmith, A.M.Edwards,C.Bountra,J.Weigelt,A.Bochkarev,H.Park, Structural Genomics Consortium (Sgc)

Key ref:
l.nedyalkova et al. crystal structure of the rhogef domain of human neuroepithelial cell-transforming gene 1 protein. TO BE PUBLISHED, .

Date:
26-Sep-08

Release date:
07-Oct-08
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