PDBsum entry 3ej2

Hydrolase

PDB id: 3ej2

Contents

Protein chain

182 a.a. *

Ligands

928

Waters ×66

* Residue conservation analysis

PDB id:

3ej2

Name:

Hydrolase

Title:

Crystal structure of inorganic pyrophosphatase from burkholderia pseudomallei with bound 5-amino-1-(4-chlorophenyl)-1h-pyrazole-4- carbonitrile, h32 crystal form

Structure:

Inorganic pyrophosphatase. Chain: a. Engineered: yes

Source:

Burkholderia pseudomallei 1710b. Organism_taxid: 320372. Gene: ppa, burps1710b_1237. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

2.12Å R-factor: 0.205 R-free: 0.249

Authors:

Seattle Structural Genomics Center For Infectious Disease (Ssgcid)

Key ref:

L.Baugh et al. (2013). Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, e53851. PubMed id: 23382856

Date:

17-Sep-08 Release date: 30-Sep-08

Protein chain

Q3JUV5  (Q3JUV5_BURP1) -  Inorganic pyrophosphatase from Burkholderia pseudomallei (strain 1710b)

Seq: 175 a.a.

Struc: 182 a.a.

Enzyme reactions

• Enzyme class: E.C.3.6.1.1 - inorganic diphosphatase.
• Reaction: diphosphate + H2O = 2 phosphate + H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

Added reference

Plos One 8:e53851 (2013)

PubMed id: 23382856

Combining functional and structural genomics to sample the essential Burkholderia structome.

L.Baugh, L.A.Gallagher, R.Patrapuvich, M.C.Clifton, A.S.Gardberg, T.E.Edwards, B.Armour, D.W.Begley, S.H.Dieterich, D.M.Dranow, J.Abendroth, J.W.Fairman, D.Fox, B.L.Staker, I.Phan, A.Gillespie, R.Choi, S.Nakazawa-Hewitt, M.T.Nguyen, A.Napuli, L.Barrett, G.W.Buchko, R.Stacy, P.J.Myler, L.J.Stewart, C.Manoil, W.C.Van Voorhis.

ABSTRACT

No abstract given.