spacer
spacer

PDBsum entry 3eim

Go to PDB code: 
protein ligands metals links
Hydrolase PDB id
3eim
Jmol
Contents
Protein chain
316 a.a. *
Ligands
GOL
Metals
CU1
_CA ×4
Waters ×209
* Residue conservation analysis
PDB id:
3eim
Name: Hydrolase
Title: Metal exchange in thermolysin
Structure: Thermolysin. Chain: a. Fragment: unp residues 233-548. Synonym: thermostable neutral proteinase. Ec: 3.4.24.27
Source: Bacillus thermoproteolyticus. Organism_taxid: 1427
Resolution:
1.88Å     R-factor:   0.188     R-free:   0.252
Authors: L.Englert,A.Heine,G.Klebe
Key ref: L.Englert et al. Metal exchange in thermolysin. To be published, .
Date:
16-Sep-08     Release date:   06-Oct-09    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P00800  (THER_BACTH) -  Thermolysin
Seq:
Struc:
 
Seq:
Struc:
548 a.a.
316 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 2 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: E.C.3.4.24.27  - Thermolysin.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Preferential cleavage: Xaa-|-Leu > Xaa-|-Phe.
      Cofactor: Ca(2+); Zn(2+)
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     proteolysis   1 term 
  Biochemical function     metalloendopeptidase activity     1 term