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Hydrolase activator PDB id
3dzx
Jmol
Contents
Protein chain
278 a.a. *
Ligands
UNX ×5
Waters ×8
* Residue conservation analysis
PDB id:
3dzx
Name: Hydrolase activator
Title: Crystal structure of the rabgap domain of human tbc1d22b
Structure: Tbc1 domain family member 22b. Chain: a. Fragment: rab-gap tbc domain, unp residues 178-505. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: tbc1d22b, c6orf197. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.30Å     R-factor:   0.235     R-free:   0.291
Authors: L.Nedyalkova,Y.Tong,W.Tempel,Y.Shen,F.Mackenzie,C.H.Arrowsmi A.M.Edwards,C.Bountra,M.Wilkstrom,A.Bochkarev,H.Park,Struct Genomics Consortium (Sgc)
Key ref: L.Nedyalkova et al. Crystal structure of the rabgap domain of human tbc1d22b. To be published,
Date:
30-Jul-08     Release date:   19-Aug-08    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q9NU19  (TB22B_HUMAN) -  TBC1 domain family member 22B
Seq:
Struc:
505 a.a.
278 a.a.
Key:    PfamA domain  Secondary structure

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     intracellular   1 term 
  Biological process     regulation of Rab GTPase activity   1 term 
  Biochemical function     Rab GTPase activator activity     1 term