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Transcription PDB id
3dm1
Jmol
Contents
Protein chains
52 a.a. *
Ligands
LYS-VAL-HIS-ARG-
ALA-ARG-M3L-THR
VAL-HIS-ARG-ALA-
ARG-M3L-THR-MET-
SER-LYS
LYS-VAL-HIS-ARG-
ALA-ARG-M3L-THR-
MET
LYS-VAL-HIS-ARG-
ALA-ARG-M3L
Waters ×91
* Residue conservation analysis
PDB id:
3dm1
Name: Transcription
Title: Crystal structure of the complex of human chromobox homolog 3 (cbx3) with peptide
Structure: Chromobox protein homolog 3. Chain: a, c, e, g. Fragment: chromo 1 domain: residues 29-86. Synonym: heterochromatin protein 1 homolog gamma, hp1 gamma, modifier 2 protein, hech. Engineered: yes. Histone-lysine n-methyltransferase, h3 lysine-9 specific 3. Chain: b, d, f, h.
Source: Homo sapiens. Organism_taxid: 9606. Gene: cbx3. Expressed in: escherichia coli. Synthetic: yes. Other_details: synthetic peptide with the sequence matching the residues 179-190 of the human histone h3-k9 methyltransferase 3, ehmt2_human, unp entry q96kq7
Resolution:
2.40Å     R-factor:   0.222     R-free:   0.267
Authors: M.F.Amaya,M.Ravichandran,P.Loppnau,I.Kozieradzki, A.M.Edwards,C.H.Arrowsmith,J.Weigelt,C.Bountra,A.Bochkarev, J.Min,H.Ouyang,Structural Genomics Consortium (Sgc)
Key ref: M.F.Amaya et al. Crystal structure of the complex of chromobox homolog 3 (cbx3) [homo sapiens] and peptide.. To be published,
Date:
30-Jun-08     Release date:   19-Aug-08    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q13185  (CBX3_HUMAN) -  Chromobox protein homolog 3
Seq:
Struc:
183 a.a.
52 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     nucleus   2 terms 
  Biological process     chromatin assembly or disassembly   1 term 
  Biochemical function     chromatin binding     1 term