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Transcription
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PDB id
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3dm1
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Contents |
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* Residue conservation analysis
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PDB id:
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Transcription
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Title:
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Crystal structure of the complex of human chromobox homolog 3 (cbx3) with peptide
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Structure:
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Chromobox protein homolog 3. Chain: a, c, e, g. Fragment: chromo 1 domain: residues 29-86. Synonym: heterochromatin protein 1 homolog gamma, hp1 gamma, modifier 2 protein, hech. Engineered: yes. Histone-lysine n-methyltransferase, h3 lysine-9 specific 3. Chain: b, d, f, h.
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Source:
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Homo sapiens. Organism_taxid: 9606. Gene: cbx3. Expressed in: escherichia coli. Synthetic: yes. Other_details: synthetic peptide with the sequence matching the residues 179-190 of the human histone h3-k9 methyltransferase 3, ehmt2_human, unp entry q96kq7
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Resolution:
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2.40Å
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R-factor:
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0.222
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R-free:
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0.267
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Authors:
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M.F.Amaya,M.Ravichandran,P.Loppnau,I.Kozieradzki, A.M.Edwards,C.H.Arrowsmith,J.Weigelt,C.Bountra,A.Bochkarev, J.Min,H.Ouyang,Structural Genomics Consortium (Sgc)
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Key ref:
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M.F.Amaya
et al.
Crystal structure of the complex of chromobox homolog 3 (cbx3) [homo sapiens] and peptide..
To be published,
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Date:
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30-Jun-08
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Release date:
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19-Aug-08
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PROCHECK
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Headers
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References
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Q13185
(CBX3_HUMAN) -
Chromobox protein homolog 3
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Seq: Struc:
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183 a.a.
52 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Gene Ontology (GO) functional annotation
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Cellular component
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nucleus
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2 terms
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Biological process
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chromatin assembly or disassembly
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1 term
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Biochemical function
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chromatin binding
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1 term
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