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PDBsum entry 3dai

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protein ligands metals links
Signaling protein PDB id
3dai
Jmol
Contents
Protein chain
130 a.a. *
Ligands
SO4 ×2
Metals
_CL
Waters ×161
* Residue conservation analysis
PDB id:
3dai
Name: Signaling protein
Title: Crystal structure of the bromodomain of the human atad2
Structure: Atpase family aaa domain-containing protein 2. Chain: a. Fragment: residues 981-1108. Engineered: yes
Source: Homo sapiens. Organism_taxid: 9606. Gene: atad2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
1.95Å     R-factor:   0.203     R-free:   0.240
Authors: P.Filippakopoulos,T.Keates,S.Picaud,O.Fedorov,A.K.Roos,F.Von C.H.Arrowsmith,A.M.Edwards,C.Bountra,S.Knapp,Structural Gen Consortium (Sgc)
Key ref: P.Filippakopoulos et al. (2012). Histone recognition and large-scale structural analysis of the human bromodomain family. Cell, 149, 214-231. PubMed id: 22464331 DOI: 10.1016/j.cell.2012.02.013
Date:
29-May-08     Release date:   09-Sep-08    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q6PL18  (ATAD2_HUMAN) -  ATPase family AAA domain-containing protein 2
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
1390 a.a.
130 a.a.*
Key:    PfamA domain  PfamB domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 2 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: E.C.3.6.1.3  - Adenosinetriphosphatase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: ATP + H2O = ADP + phosphate
ATP
+ H(2)O
= ADP
+ phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

 
    reference    
 
 
DOI no: 10.1016/j.cell.2012.02.013 Cell 149:214-231 (2012)
PubMed id: 22464331  
 
 
Histone recognition and large-scale structural analysis of the human bromodomain family.
P.Filippakopoulos, S.Picaud, M.Mangos, T.Keates, J.P.Lambert, D.Barsyte-Lovejoy, I.Felletar, R.Volkmer, S.Müller, T.Pawson, A.C.Gingras, C.H.Arrowsmith, S.Knapp.
 
  ABSTRACT  
 
No abstract given.

 

Literature references that cite this PDB file's key reference

  PubMed id Reference
23211769 C.A.Musselman, M.E.Lalonde, J.Côté, and T.G.Kutateladze (2012).
Perceiving the epigenetic landscape through histone readers.
  Nat Struct Mol Biol, 19, 1218-1227.  
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time.