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PDBsum entry 3da2

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protein ligands metals Protein-protein interface(s) links
Lyase PDB id
3da2
Jmol
Contents
Protein chain
262 a.a. *
Ligands
4MD ×2
Metals
_ZN ×2
_CL ×2
Waters ×435
* Residue conservation analysis
PDB id:
3da2
Name: Lyase
Title: X-ray structure of human carbonic anhydrase 13 in complex wi inhibitor
Structure: Carbonic anhydrase 13. Chain: a, b. Synonym: carbonic anhydrase xiii, carbonate dehydratase xii xiii. Engineered: yes
Source: Homo sapiens. Organism_taxid: 9606. Gene: ca13. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.05Å     R-factor:   0.162     R-free:   0.221
Authors: E.S.Pilka,S.S.Picaud,W.W.Yue,O.N.F.King,J.E.Bray,P.Filippako A.K.Roos,A.C.W.Pike,F.Von Delft,C.H.Arrowsmith,M.Wikstrom, A.M.Edwards,C.Bountra,U.Oppermann,Structural Genomics Conso (Sgc)
Key ref: E.S.Pilka et al. X-Ray structure of human carbonic anhydrase 13 in complex with inhibitor.. To be published, .
Date:
28-May-08     Release date:   15-Jul-08    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q8N1Q1  (CAH13_HUMAN) -  Carbonic anhydrase 13
Seq:
Struc:
262 a.a.
262 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.4.2.1.1  - Carbonate dehydratase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: H2CO3 = CO2 + H2O
H(2)CO(3)
= CO(2)
+ H(2)O
      Cofactor: Zinc
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cytosol   1 term 
  Biological process     small molecule metabolic process   3 terms 
  Biochemical function     lyase activity     4 terms