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PDBsum entry 3czm

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protein ligands Protein-protein interface(s) links
Oxidoreductase PDB id
3czm
Jmol
Contents
Protein chains
322 a.a. *
Ligands
NAD ×2
OXQ ×2
Waters ×279
* Residue conservation analysis
PDB id:
3czm
Name: Oxidoreductase
Title: T. Gondii bradyzoite-specific ldh (ldh2) in complex with nad
Structure: L-lactate dehydrogenase. Chain: a, b. Synonym: ldh. Engineered: yes
Source: Toxoplasma gondii. Organism_taxid: 5811. Gene: lactate dehydrogenase. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.30Å     R-factor:   0.169     R-free:   0.223
Authors: D.K.Wilson,M.S.Susko
Key ref: D.K.Wilson and m.s.susko T. Gondii bradyzoite-Specific ldh (ldh2) in complex with NAD and oxq. To be published, .
Date:
29-Apr-08     Release date:   02-Jun-09    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q27797  (LDH_TOXGO) -  L-lactate dehydrogenase
Seq:
Struc:
326 a.a.
322 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

 Enzyme reactions 
   Enzyme class: E.C.1.1.1.27  - L-lactate dehydrogenase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: (S)-lactate + NAD+ = pyruvate + NADH
(S)-lactate
Bound ligand (Het Group name = OXQ)
matches with 50.00% similarity
+
NAD(+)
Bound ligand (Het Group name = NAD)
corresponds exactly
= pyruvate
+ NADH
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     oxidation-reduction process   5 terms 
  Biochemical function     catalytic activity     5 terms