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PDBsum entry 3cfr

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protein dna_rna ligands metals links
Transferase/DNA PDB id
3cfr
Jmol
Contents
Protein chain
901 a.a. *
DNA/RNA
Ligands
TTP
Metals
_CL
_CA ×5
Waters ×629
* Residue conservation analysis
PDB id:
3cfr
Name: Transferase/DNA
Title: Structure of the replicating complex of a pol alpha family DNA polymerase, ternary complex 2
Structure: DNA polymerase. Chain: a. Synonym: gp43. Engineered: yes. Mutation: yes. DNA (5'- d( Dtp Dcp Dap Dap Dgp Dtp Dap Dap Dgp Dcp Dap Dgp Dtp Dcp Dcp Dgp Dcp Dg)-3'). Chain: t.
Source: Bacteriophage rb69. Gene: 43. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthesized by w.M. Keck facility at yale university. University
Resolution:
2.40Å     R-factor:   0.196     R-free:   0.266
Authors: J.Wang,D.Klimenko,M.Wang,T.A.Steitz,W.H.Konigsberg
Key ref: D.Klimenko et al. To be published, .
Date:
04-Mar-08     Release date:   10-Mar-09    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q38087  (DPOL_BPR69) -  DNA polymerase
Seq:
Struc:
 
Seq:
Struc:
903 a.a.
901 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 3 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: E.C.2.7.7.7  - DNA-directed Dna polymerase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Deoxynucleoside triphosphate
Bound ligand (Het Group name = TTP)
matches with 66.00% similarity
+ DNA(n)
= diphosphate
+ DNA(n+1)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     DNA biosynthetic process   4 terms 
  Biochemical function     nucleotide binding     9 terms