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PDBsum entry 3bl1

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protein ligands metals links
Lyase PDB id
3bl1
Jmol
Contents
Protein chain
256 a.a. *
Ligands
BL1
Metals
_ZN
_HG
Waters ×163
* Residue conservation analysis
PDB id:
3bl1
Name: Lyase
Title: Carbonic anhydrase inhibitors. Sulfonamide diuretics revisited old leads for new applications
Structure: Carbonic anhydrase 2. Chain: a. Synonym: carbonic anhydrase ii, carbonate dehydratase ii, ca-ii, carbonic anhydrasE C. Ec: 4.2.1.1
Source: Homo sapiens. Human
Resolution:
2.10Å     R-factor:   0.228     R-free:   0.299
Authors: C.Temperini,A.Cecchi,C.T.Supuran
Date:
10-Dec-07     Release date:   01-Jul-08    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P00918  (CAH2_HUMAN) -  Carbonic anhydrase 2
Seq:
Struc:
260 a.a.
256 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.4.2.1.1  - Carbonate dehydratase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: H2CO3 = CO2 + H2O
H(2)CO(3)
= CO(2)
+ H(2)O
      Cofactor: Zn(2+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     extracellular space   11 terms 
  Biological process     angiotensin-mediated signaling pathway   21 terms 
  Biochemical function     protein binding     5 terms