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Residue conservation analysis
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| PDB id: |
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3baa
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| Name: |
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Ligase
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| Title: |
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Structural basis for the inhibition of bacterial NAD+ dependent DNA ligase
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 Structure: |
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DNA ligase. Chain: a. Fragment: adenylation domain. Engineered: yes
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Source:
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Enterococcus faecalis. Streptococcus faecalis. Organism_taxid: 1351. Gene: liga. Expressed in: escherichia coli. Expression_system_taxid: 562
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UniProt:
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| Seq: |
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| Struc: |
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| Seq: |
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| Struc: |
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| Seq: |
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676 a.a. |
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| Struc: |
312 a.a. |
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| Key: |
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PfamA domain |
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Secondary structure |
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Enzyme class:
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Reaction:
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NAD+ + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + nicotinamide nucleotide + (deoxyribonucleotide)(n+m)
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Resolution:
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1.90Å
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R-factor:
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0.187
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R-free:
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0.216
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Authors:
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C.Pinko
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Key ref:
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c.pinko
et al.
structural basis for the inhibition of bacterial nad+ dependent dna ligase.
TO BE PUBLISHED,
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Date:
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07-Nov-07
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Release date:
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11-Nov-08
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Related entries:
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