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PDBsum entry 3ak2

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protein ligands metals Protein-protein interface(s) links
Oxidoreductase PDB id
3ak2
Jmol
Contents
Protein chains
211 a.a. *
Ligands
EDO ×18
Metals
_MN ×4
Waters ×734
* Residue conservation analysis
PDB id:
3ak2
Name: Oxidoreductase
Title: Superoxide dismutase from aeropyrum pernix k1, mn-bound form
Structure: Superoxide dismutase [mn/fe]. Chain: a, b, c, d. Engineered: yes
Source: Aeropyrum pernix. Organism_taxid: 272557. Strain: k1. Gene: ape0741. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
1.35Å     R-factor:   0.188     R-free:   0.203
Authors: T.Nakamura,K.Uegaki
Key ref: T.Nakamura et al. (2011). Crystal structure of the cambialistic superoxide dismutase from Aeropyrum pernix K1--insights into the enzyme mechanism and stability. FEBS J, 278, 598-609. PubMed id: 21182595
Date:
30-Jun-10     Release date:   02-Feb-11    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q9Y8H8  (SODF_AERPE) -  Superoxide dismutase [Mn/Fe]
Seq:
Struc:
214 a.a.
211 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.1.15.1.1  - Superoxide dismutase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: 2 superoxide + 2 H+ = O2 + H2O2
2 × superoxide
+ 2 × H(+)
= O(2)
+ H(2)O(2)
      Cofactor: Fe cation or Mn(2+) or (Zn(2+) and Cu cation)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     oxidation-reduction process   3 terms 
  Biochemical function     oxidoreductase activity     4 terms  

 

 
    Added reference    
 
 
FEBS J 278:598-609 (2011)
PubMed id: 21182595  
 
 
Crystal structure of the cambialistic superoxide dismutase from Aeropyrum pernix K1--insights into the enzyme mechanism and stability.
T.Nakamura, K.Torikai, K.Uegaki, J.Morita, K.Machida, A.Suzuki, Y.Kawata.
 
  ABSTRACT  
 
No abstract given.