spacer
spacer

PDBsum entry 3ae3

Go to PDB code: 
protein ligands Protein-protein interface(s) links
Oxidoreductase/oxidoreductase inhibitor PDB id
3ae3
Jmol
Contents
Protein chains
613 a.a. *
239 a.a. *
138 a.a. *
102 a.a. *
Ligands
FAD
FES
SF4
F3S
HEM
EPH
NBI
* Residue conservation analysis
PDB id:
3ae3
Name: Oxidoreductase/oxidoreductase inhibitor
Title: Crystal structure of porcine heart mitochondrial complex ii 2-nitro-n-phenyl-benzamide
Structure: Succinate dehydrogenase [ubiquinone] flavoprotein mitochondrial. Chain: a. Synonym: flavoprotein subunit of complex ii, fp. Succinate dehydrogenase [ubiquinone] iron-sulfur mitochondrial. Chain: b. Synonym: iron-sulfur subunit of complex ii, ip. Succinate dehydrogenase cytochrome b560 subunit,
Source: Sus scrofa. Pig. Organism_taxid: 9823. Organ: heart. Tissue: muscle. Tissue: muscle
Resolution:
3.35Å     R-factor:   0.216     R-free:   0.261
Authors: S.Harada,T.Sasaki,M.Shindo,Y.Kido,D.K.Inaoka,J.Omori,A.Osana K.Sakamoto,J.Mao,S.Matsuoka,M.Inoue,T.Honma,A.Tanaka,K.Kita
Key ref: S.Harada et al. Crystal structure of porcine heart mitochondrial comp bound with 2-Nitro-N-Phenyl-Benzamide. To be published, .
Date:
04-Feb-10     Release date:   09-Feb-11    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q0QF01  (DHSA_PIG) -  Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Seq:
Struc:
 
Seq:
Struc:
664 a.a.
613 a.a.
Protein chain
Pfam   ArchSchema ?
Q007T0  (DHSB_PIG) -  Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Seq:
Struc:
280 a.a.
239 a.a.
Protein chain
Pfam   ArchSchema ?
D0VWV4  (C560_PIG) -  Succinate dehydrogenase cytochrome b560 subunit, mitochondrial
Seq:
Struc:
169 a.a.
138 a.a.
Protein chain
Pfam   ArchSchema ?
A5GZW8  (DHSD_PIG) -  Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial
Seq:
Struc:
159 a.a.
102 a.a.*
Key:    PfamA domain  PfamB domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

 Enzyme reactions 
   Enzyme class: Chains A, B: E.C.1.3.5.1  - Succinate dehydrogenase (quinone).
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

      Pathway:
Citric acid cycle
      Reaction: Succinate + a quinone = fumarate + a quinol
Succinate
+ quinone
= fumarate
+ quinol
      Cofactor: FAD; Iron-sulfur
FAD
Bound ligand (Het Group name = FAD) corresponds exactly
Iron-sulfur
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     membrane   7 terms 
  Biological process     oxidation-reduction process   3 terms 
  Biochemical function     electron carrier activity     13 terms