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PDBsum entry 3rf3

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protein ligands Protein-protein interface(s) links
Protein binding/toxin PDB id
3rf3
Jmol
Contents
Protein chains
257 a.a.
23 a.a.
24 a.a.
Ligands
CAC ×2
Waters ×804
PDB id:
3rf3
Name: Protein binding/toxin
Title: Shigella ipaa-vbs3 in complex with human vinculin
Structure: Vinculin. Chain: a, b. Fragment: unp residues 1-258. Synonym: metavinculin. Engineered: yes. Invasin ipaa. Chain: c, d. Fragment: unp residues 488-512. Synonym: 70 kda antigen.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: vcl, vinculin. Expressed in: escherichia coli. Expression_system_taxid: 469008. Shigella flexneri. Organism_taxid: 623. Gene: cp0125, ipaa.
Resolution:
1.61Å     R-factor:   0.184     R-free:   0.195
Authors: H.Park,A.Sharff,T.Izard
Key ref: H.Park et al. (2011). Novel vinculin binding site of the IpaA invasin of Shigella. J Biol Chem, 286, 23214-23221. PubMed id: 21525010
Date:
05-Apr-11     Release date:   27-Apr-11    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
P18206  (VINC_HUMAN) -  Vinculin
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
1134 a.a.
257 a.a.
Protein chain
Pfam   ArchSchema ?
P18010  (IPAA_SHIFL) -  Invasin IpaA
Seq:
Struc:
 
Seq:
Struc:
633 a.a.
23 a.a.
Protein chain
Pfam   ArchSchema ?
P18010  (IPAA_SHIFL) -  Invasin IpaA
Seq:
Struc:
 
Seq:
Struc:
633 a.a.
24 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     actin cytoskeleton   1 term 
  Biological process     cell adhesion   1 term 
  Biochemical function     structural molecule activity     1 term  

 

 
J Biol Chem 286:23214-23221 (2011)
PubMed id: 21525010  
 
 
Novel vinculin binding site of the IpaA invasin of Shigella.
H.Park, C.Valencia-Gallardo, A.Sharff, G.Tran Van Nhieu, T.Izard.
 
  ABSTRACT  
 
No abstract given.