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PDBsum entry 3ohl

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protein ligands metals links
Hydrolase/hydrolase inhibitor PDB id
3ohl
Jmol
Contents
Protein chain
159 a.a.
Ligands
OHL
SO4
Metals
_CA ×3
_ZN ×2
Waters ×16
PDB id:
3ohl
Name: Hydrolase/hydrolase inhibitor
Title: Catalytic domain of stromelysin-1 in complex with n-hydroxy- methoxy-n-(pyridine-3-ylmethyl)phenylsulfonamido)acetamide
Structure: Stromelysin-1. Chain: a. Fragment: unp residues 100-266. Synonym: sl-1, matrix metalloproteinase-3, mmp-3, transin-1 engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mmp3, stmy1. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Resolution:
2.36Å     R-factor:   0.262     R-free:   0.283
Authors: T.Kowatz,J.H.Naismith
Key ref: T.Kowatz and j.h.naismith Non-Resonance raman difference spectroscopy as a tool probe enthalpy-Entropy compensation and the interfaci mobility model. To be published, .
Date:
17-Aug-10     Release date:   29-Jun-11    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P08254  (MMP3_HUMAN) -  Stromelysin-1
Seq:
Struc:
477 a.a.
159 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.3.4.24.17  - Stromelysin 1.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Preferential cleavage where P1', P2' and P3' are hydrophobic residues.
      Cofactor: Ca(2+); Zn(2+)
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     extracellular matrix   1 term 
  Biological process     proteolysis   1 term 
  Biochemical function     metallopeptidase activity     3 terms