PDBsum entry: 3knu

Transferase

PDB id: 3knu

Contents

Protein chains

192 a.a. *

199 a.a. *

Waters ×336

* Residue conservation analysis

PDB id:

3knu

Name:

Transferase

Title:

Crystal structure of tRNA (guanine-n1)-methyltransferase fro anaplasma phagocytophilum

Structure:

tRNA (guanine-n(1)-)-methyltransferase. Chain: a, b, c, d. Synonym: m1g-methyltransferase, tRNA [gm37] methyltransfera engineered: yes

Source:

Anaplasma phagocytophilum. Organism_taxid: 212042. Strain: hz. Gene: trmd, aph_1267. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

2.25Å R-factor: 0.205 R-free: 0.234

Authors:

Seattle Structural Genomics Center For Infectious Disease (S

Key ref:

T.E.Edwards et al. Crystal structure of tRNA (guanine-N1)-Methyltransferase from anaplasma phagocytophilum. To be published,

Date:

12-Nov-09 Release date: 24-Nov-09

Protein chains

Q2GIL5  (TRMD_ANAPZ) -  tRNA (guanine-N(1)-)-methyltransferase

Seq: 232 a.a.

Struc: 192 a.a.

Protein chains

Q2GIL5  (TRMD_ANAPZ) -  tRNA (guanine-N(1)-)-methyltransferase

Seq: 232 a.a.

Struc: 199 a.a.

Enzyme reactions

• Enzyme class: Chains A, B, C, D: E.C.2.1.1.228 - tRNA (guanine(37)-N(1))-methyltransferase.
• Reaction: S-adenosyl-L-methionine + guanine₃₇ in tRNA = S-adenosyl-L-homocysteine + N₁-methylguanine₃₇ in tRNA

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 Gene Ontology (GO) functional annotation 

• Cellular component: cytoplasm (1 term)
• Biological process: methylation (2 terms)
• Biochemical function: transferase activity (4 terms)