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Hydrolase PDB-id
3iv8
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Contents
Description
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Protein chains
379 a.a. *
356 a.a. *
Ligands
F6P
SO4 ×3
Metal ions
_NI ×4
Waters ×332

* Residue conservation analysis
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PDB id: 3iv8
Name: Hydrolase
Title: N-acetylglucosamine-6-phosphate deacetylase from vibrio cholerae complexed with fructose 6-phosphate

Structure:
N-acetylglucosamine-6-phosphate deacetylase. Chain: a, b, c, d. Synonym: glcnac 6-p deacetylase. Engineered: yes

Source:
Vibrio cholerae. Organism_taxid: 666. Strain: o1 biovar el tor str. N16961. Gene: naga, vc_0994. Expressed in: escherichia coli. Expression_system_taxid: 562.

Enzyme class:
Chains A, B, C: E.C.3.5.1.25   [IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

Reaction:
N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate (see diagram below)

Pathway:
UDP-N-acetylglucosamine Biosynthesis

Resolution:
2.53Å

R-factor:
0.186

R-free:
0.253

Authors:
J.Osipiuk,N.Maltseva,J.Stam,W.F.Anderson,A.Joachimiak,Center For Structural Genomics Of Infectious Diseases (Csgid)

Date:
31-Aug-09

Release date:
08-Sep-09

Related entries:
3egj
n-acetylglucosamine-6-phosphate deacetylase from vibrio
cholerae
idp01334 related db: targetdb
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Enzyme reaction for E.C.3.5.1.25


N-acetyl-D-glucosamine 6-phosphate
+ H(2)O
=
D-glucosamine 6-phosphate
+
acetate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.