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Hydrolase PDB id
3ico
Jmol
Contents
Protein chains
244 a.a. *
Ligands
SO4 ×6
Waters ×496
* Residue conservation analysis
PDB id:
3ico
Name: Hydrolase
Title: Crystal structure of 6-phosphogluconolactonase from mycobacterium tuberculosis
Structure: 6-phosphogluconolactonase. Chain: a, b, c, d. Synonym: 6pgl. Engineered: yes
Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Gene: pgl, devb, rv1445c, mt1492, mtcy493.09. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.15Å     R-factor:   0.184     R-free:   0.223
Authors: Seattle Structural Genomics Center For Infectious Disease (Ssgcid)
Key ref: T.E.Edwards et al. Crystal structure of 6-Phosphogluconolactonase from mycobacterium tuberculosis. To be published,
Date:
17-Jul-09     Release date:   28-Jul-09    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
P63338  (6PGL_MYCTU) -  6-phosphogluconolactonase
Seq:
Struc: 		247 a.a.
244 a.a.
Key:    PfamA domain  Secondary structure

 Enzyme reactions 
   Enzyme class: E.C.3.1.1.31  - 6-phosphogluconolactonase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

      Pathway: 		Pentose Phosphate Pathway (early stages)
      Reaction: 6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate
6-phospho-D-glucono-1,5-lactone
 + H(2)O
 = 6-phospho-D-gluconate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     plasma membrane   1 term 
  Biological process     pentose-phosphate shunt   1 term 
  Biochemical function     hydrolase activity     2 terms