PDBsum entry: 3ico

Hydrolase

PDB-id: 3ico

Contents

Description

Header details

Header records

References

PROCHECK

Protein chains

244 a.a. *

Ligands

SO4 ×6

Waters ×496

* Residue conservation analysis

Tools

Clefts Calculation

PDB id:

3ico

Name:

Hydrolase

Title:

Crystal structure of 6-phosphogluconolactonase from mycobacterium tuberculosis

Structure:

6-phosphogluconolactonase. Chain: a, b, c, d. Synonym: 6pgl. Engineered: yes

Source:

Mycobacterium tuberculosis. Organism_taxid: 1773. Gene: pgl, devb, rv1445c, mt1492, mtcy493.09. Expressed in: escherichia coli. Expression_system_taxid: 562.

UniProt:

Chain : ()

Enzyme class:

E.C.3.1.1.31   [IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

Reaction:

6-phospho-D-glucono-1,5-lactone + H₂O = 6-phospho-D-gluconate (see diagram below)

Pathway:

Pentose Phosphate Pathway (early stages)

Resolution:

2.15Å

R-factor:

0.184

R-free:

0.223

Authors:

Seattle Structural Genomics Center For Infectious Disease (Ssgcid)

Key ref:

t.e.edwards et al. crystal structure of 6-phosphogluconolactonase from mycobacterium tuberculosis. TO BE PUBLISHED, .

Date:

17-Jul-09

Release date:

28-Jul-09

Related entries:

Mytud.01244.A related db: targetdb

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