 |
 |
|
|
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 | | Sugar binding protein, lyase
| PDB-id |
|
 |
 |
3e7j |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |

*
Residue conservation analysis
|
|
| PDB id: |
 |
3e7j
|
 |
| Name: |
 |
Sugar binding protein, lyase
|
 |
| Title: |
 |
Heparinaseii h202a/y257a double mutant complexed with a heparan sulfate tetrasaccharide substrate
|
 |
 Structure: |
 |
Heparinase ii protein. Chain: a, b. Fragment: unp residues 24-772. Mutation: yes
|
 |

Source:
|
 |
Pedobacter heparinum. Organism_taxid: 984
|
 |

UniProt:
|
 |
|
Chains A,
B:
Q46080
(Q46080_PEDHE)
|
| Seq: |
 |
 |
 |
 |
|
| Struc: |
 |
 |
 |
| Seq: |
 |
 |
 |
 |
|
| Struc: |
 |
 |
 |
| Seq: |
 |
 |
 |
 |
|
| Struc: |
 |
 |
 |
| Seq: |
 |
 |
 |
772 a.a. |
|
| Struc: |
743 a.a.* |
 |
 |
 |
| Key: |
 |
PfamA domain |
 |
 |
PfamB domain |
 |
 |
 |
Secondary structure |
 |
 |
|
|
 |
|
* PDB and UniProt seqs differ
at 3 residue positions (black
crosses)
|
|
 |

Resolution:
|
 |
2.10Å
|
 |

R-factor:
|
 |
0.201
|
 |

R-free:
|
 |
0.234
|
 |

Authors:
|
 |
D.Shaya,M.Cygler
|
 |

Key ref:
|
 |
d.shaya
and
m.cygler
HeparinaseII H202A/Y257A double mutant complexed with a heparan sulfate tetrasaccharide substrate.
TO BE PUBLISHED,
xsi:nil="true" />.
|
 |

Date:
|
 |
18-Aug-08
|
 |

Release date:
|
 |
30-Dec-08
|
 |

Related entries:
|
 |
heparinase ii complexed with heparan sulfate degradation
disaccharide product
|
 |
|
|
|
 |
Quick_links |
 |
 |
Procheck |
 |
 |
Clefts |
 |
 |
Surface |
 |
|
|