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PDBsum entry 3bel

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protein ligands links
Transferase PDB id
3bel
Jmol
Contents
Protein chain
280 a.a. *
Ligands
PO4 ×2
POX
Waters ×27
* Residue conservation analysis
PDB id:
3bel
Name: Transferase
Title: X-ray structure of egfr in complex with oxime inhibitor
Structure: Epidermal growth factor receptor. Chain: a. Fragment: residues 702-1016. Synonym: receptor tyrosine-protein kinase erbb-1. Engineered: yes
Source: Homo sapiens. Human. Strain: human strains undefined. Gene: egfr, erbb1. Expressed in: spodoptera frugiperda.
Resolution:
2.30Å     R-factor:   0.241     R-free:   0.281
Authors: M.C.Abad,G.Xu,M.P.Neeper,G.T.Struble,M.D.Gaul,P.J.Connolly
Date:
19-Nov-07     Release date:   01-Jul-08    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P00533  (EGFR_HUMAN) -  Epidermal growth factor receptor
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
1210 a.a.
280 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.2.7.10.1  - Receptor protein-tyrosine kinase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
ATP
+ [protein]-L-tyrosine
= ADP
+ [protein]-L-tyrosine phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     protein phosphorylation   1 term 
  Biochemical function     transferase activity, transferring phosphorus-containing groups     4 terms