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PDBsum entry 3av2

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protein dna_rna Protein-protein interface(s) links
Structural protein/DNA PDB id
3av2
Jmol
Contents
Protein chains
97 a.a.
78 a.a.
105 a.a.
94 a.a.
84 a.a.
DNA/RNA
Waters ×84
PDB id:
3av2
Name: Structural protein/DNA
Title: The human nucleosome structure containing the histone varian
Structure: Histone h3.3. Chain: a, e. Synonym: histone h3/m, histone h3/o. Engineered: yes. Histone h4. Chain: b, f. Engineered: yes. Histone h2a type 1-b/e. Chain: c, g.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3.3. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: h4. Gene: h2a. Gene: h2b.
Resolution:
2.80Å     R-factor:   0.230     R-free:   0.272
Authors: H.Tachiwana,A.Osakabe,T.Shiga,M.Miya,H.Kimura,W.Kagawa,H.Kur
Key ref: H.Tachiwana et al. (2011). Structures of human nucleosomes containing major histone H3 variants. Acta Crystallogr D Biol Crystallogr, 67, 578-583. PubMed id: 21636898
Date:
18-Feb-11     Release date:   01-Jun-11    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
P84243  (H33_HUMAN) -  Histone H3.3
Seq:
Struc:
136 a.a.
97 a.a.
Protein chain
Pfam   ArchSchema ?
P62805  (H4_HUMAN) -  Histone H4
Seq:
Struc:
103 a.a.
78 a.a.
Protein chains
Pfam   ArchSchema ?
P04908  (H2A1B_HUMAN) -  Histone H2A type 1-B/E
Seq:
Struc:
130 a.a.
105 a.a.
Protein chains
Pfam   ArchSchema ?
P06899  (H2B1J_HUMAN) -  Histone H2B type 1-J
Seq:
Struc:
126 a.a.
94 a.a.
Protein chain
Pfam   ArchSchema ?
P62805  (H4_HUMAN) -  Histone H4
Seq:
Struc:
103 a.a.
84 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     extracellular region   11 terms 
  Biological process     histone H4-K20 demethylation   19 terms 
  Biochemical function     RNA polymerase II core promoter sequence-specific DNA binding     8 terms  

 

 
Acta Crystallogr D Biol Crystallogr 67:578-583 (2011)
PubMed id: 21636898  
 
 
Structures of human nucleosomes containing major histone H3 variants.
H.Tachiwana, A.Osakabe, T.Shiga, Y.Miya, H.Kimura, W.Kagawa, H.Kurumizaka.
 
  ABSTRACT  
 
No abstract given.

 

Literature references that cite this PDB file's key reference

  PubMed id Reference
23142979 C.P.Liu, C.Xiong, M.Wang, Z.Yu, N.Yang, P.Chen, Z.Zhang, G.Li, and R.M.Xu (2012).
Structure of the variant histone H3.3-H4 heterodimer in complex with its chaperone DAXX.
  Nat Struct Mol Biol, 19, 1287-1292.  
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time.