PDBsum entry: 2zqk

Cell adhesion

PDB id: 2zqk

Contents

Protein chains

183 a.a. *

64 a.a. *

* Residue conservation analysis

PDB id:

2zqk

Name:

Cell adhesion

Title:

Crystal structure of intimin-tir68 complex

Structure:

Intimin. Chain: a, b. Fragment: d2-d3 domain, unp residues 747-934. Synonym: attaching and effacing protein, eae protein, gamma-intimin. Engineered: yes. Putative translocated intimin receptor protein (translocated intimin receptor tir). Chain: m, n, c, d.

Source:

Escherichia coli. Organism_taxid: 83334. Strain: o157:h7 edl933. Gene: intimin adherence protein 747-934. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: tir 269-336.

Resolution:

2.80Å R-factor: 0.241 R-free: 0.300

Authors:

Y.Ma,F.Gao,D.-F.Li,G.F.Gao

Key ref:

Y.Ma et al. Structural insight into the interaction between intimin and tir of enterohaemorrhagic e coli: evidence for a dynamic sequential clustering-Aggregating-Reticulating model. To be published,

Date:

12-Aug-08 Release date: 18-Aug-09

Protein chains

P43261  (EAE_ECO57) -  Intimin

Seq: 934 a.a.

Struc: 183 a.a.

Protein chains

Q7DB77  (Q7DB77_ECO57) -  Translocated intimin receptor Tir

Seq: 558 a.a.

Struc: 64 a.a.

 Gene Ontology (GO) functional annotation 

• Cellular component: cell surface (1 term)
• Biological process: pathogenesis (1 term)
• Biochemical function: binding (2 terms)