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PDBsum entry 2zla

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protein ligands Protein-protein interface(s) links
Hormone PDB id
2zla
Jmol
Contents
Protein chains
238 a.a. *
11 a.a. *
Ligands
VDB
Waters ×176
* Residue conservation analysis
PDB id:
2zla
Name: Hormone
Title: 2-substituted-16-ene-22-thia-1alpha,25-dihydroxy-26,27- dimethyl-19-norvitamin d3 analogs: synthesis, biological evaluation and crystal structure
Structure: Vitamin d3 receptor. Chain: a. Fragment: vdr-lbd, unp residues 116-423. Synonym: ligand binding domain of vitamin d receptor, vdr, 1,25-dihydroxyvitamin d3 receptor, nuclear receptor subfamily 1 group i member 1. Engineered: yes. Coactivator peptide drip. Chain: c.
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: vdr, nr1i1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: peptide synthesis
Resolution:
2.00Å     R-factor:   0.213     R-free:   0.263
Authors: M.Shimizu,Y.Miyamoto,M.Nakabayashi,H.Masuno,T.Ikura,N.Ito
Date:
04-Apr-08     Release date:   24-Jun-08    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
P13053  (VDR_RAT) -  Vitamin D3 receptor
Seq:
Struc:
423 a.a.
238 a.a.
Protein chain
No UniProt id for this chain
Struc: 11 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     nucleus   1 term 
  Biological process     steroid hormone mediated signaling pathway   2 terms 
  Biochemical function     DNA binding     4 terms