spacer
spacer

PDBsum entry 2zfs
Go to PDB code: 
protein ligands metals links
Hydrolase/hydrolase inhibitor PDB id
2zfs

 

 

 

 

Loading ...

 
JSmol PyMol  
Contents
Protein chain
223 a.a. *
Ligands
12U
DMS
GOL
Metals
_CA
Waters ×199
* Residue conservation analysis
PDB id:
2zfs
Name: Hydrolase/hydrolase inhibitor
Title: Exploring trypsin s3 pocket
Structure: Cationic trypsin. Chain: a. Ec: 3.4.21.4
Source: Bos taurus. Bovine. Organism_taxid: 9913. Tissue: pancreas
Resolution:
1.51Å     R-factor:   0.139     R-free:   0.191
Authors: T.Brandt,B.Baum,A.Heine,G.Klebe
Key ref: T.Brandt et al. (2011). Congeneric but still distinct: how closely related trypsin ligands exhibit different thermodynamic and structural properties. J Mol Biol, 405, 1170-1187. PubMed id: 21111747
Date:
10-Jan-08     Release date:   13-Jan-09    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P00760  (TRY1_BOVIN) -  Serine protease 1 from Bos taurus
Seq:
Struc: 		246 a.a.
223 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.3.4.21.4  - trypsin.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.

 

 
J Mol Biol 405:1170-1187 (2011)
PubMed id: 21111747  
 
 
Congeneric but still distinct: how closely related trypsin ligands exhibit different thermodynamic and structural properties.
T.Brandt, N.Holzmann, L.Muley, M.Khayat, C.Wegscheid-Gerlach, B.Baum, A.Heine, D.Hangauer, G.Klebe.
 
  ABSTRACT  
 
No abstract given.

 

 

spacer
spacer