spacer
spacer

PDBsum entry 2yqw

Go to PDB code: 
protein metals Protein-protein interface(s) links
Oxidoreductase PDB id
2yqw
Jmol
Contents
Protein chains
153 a.a.
118 a.a.
Metals
_ZN ×4
_CU ×4
Waters ×29
Superseded by: 2zkx
PDB id:
2yqw
Name: Oxidoreductase
Title: Crystal structure of human cu-zn superoxide dismutase mutant g85r (i212121)
Structure: Superoxide dismutase [cu-zn]. Chain: a, b, c, d. Engineered: yes. Mutation: yes
Source: Homo sapiens. Human. Gene: sod1. Expressed in: escherichia coli.
Resolution:
2.72Å     R-factor:   0.176     R-free:   0.248
Authors: S.Yoshikawa,K.Ito,M.Kukimoto-Niino,L.Chen,Z.Q.Fu,J.Chrzas, B.C.Wang,M.Shirouzu,R.Takahashi,S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)
Key ref: S.Yoshikawa et al. Crystal structure of human cu-Zn superoxide dismutase mutant g85r (i212121). To be published, .
Date:
31-Mar-07     Release date:   01-Apr-08    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
P00441  (SODC_HUMAN) -  Superoxide dismutase [Cu-Zn]
Seq:
Struc:
154 a.a.
153 a.a.*
Protein chain
Pfam   ArchSchema ?
P00441  (SODC_HUMAN) -  Superoxide dismutase [Cu-Zn]
Seq:
Struc:
154 a.a.
118 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 2 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: Chains A, B, C: E.C.1.15.1.1  - Superoxide dismutase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: 2 superoxide + 2 H+ = O2 + H2O2
2 × superoxide
+ 2 × H(+)
= O(2)
+ H(2)O(2)
      Cofactor: Fe cation or Mn(2+) or (Zn(2+) and Cu cation)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site