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PDBsum entry 2yfg

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protein ligands Protein-protein interface(s) links
Oxidoreductase PDB id
2yfg
Jmol
Contents
Protein chains
(+ 0 more) 442 a.a.
Ligands
GOL ×4
Waters ×703
Superseded by: 4bht
PDB id:
2yfg
Name: Oxidoreductase
Title: Structural determinants of cofactor specificity and domain flexibility in bacterial glutamate dehydrogenases
Structure: NADP-specific glutamate dehydrogenase. Chain: a, b, c, d, f. Engineered: yes. NADP-specific glutamate dehydrogenase. Chain: e. Engineered: yes
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
Resolution:
2.50Å     R-factor:   0.176     R-free:   0.250
Authors: T.Oliveira,M.A.Sharkey,M.Hamza,P.C.Engel,A.R.Khan
Key ref: T.Oliveira et al. Structural determinants of cofactor specificity and d flexibility in bacterial glutamate dehydrogenases. To be published, .
Date:
05-Apr-11     Release date:   28-Mar-12    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
P00370  (DHE4_ECOLI) -  NADP-specific glutamate dehydrogenase
Seq:
Struc:
447 a.a.
442 a.a.
Key:    PfamA domain  PfamB domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.1.4.1.4  - Glutamate dehydrogenase (NADP(+)).
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH
L-glutamate
+ H(2)O
+ NADP(+)
=
2-oxoglutarate
Bound ligand (Het Group name = GOL)
matches with 45.45% similarity
+ NH(3)
+ NADPH
Molecule diagrams generated from .mol files obtained from the KEGG ftp site