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PDBsum entry 2y78

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protein ligands metals links
Isomerase PDB id
2y78
Jmol
Contents
Protein chain
122 a.a.
Ligands
SO4 ×2
GOL ×2
Metals
_CL
Waters ×275
PDB id:
2y78
Name: Isomerase
Title: Crystal structure of bpss1823, a mip-like chaperone from burkholderia pseudomallei
Structure: Peptidyl-prolyl cis-trans isomerase. Chain: a. Synonym: prolyl-peptide isomerase. Engineered: yes
Source: Burkholderia pseudomallei. Organism_taxid: 272560. Strain: k96243. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
0.91Å     R-factor:   0.109     R-free:   0.116
Authors: I.H.Norville,K.O'Shea,M.Sarkar-Tyson,N.J.Harmer
Key ref: I.H.Norville et al. (2011). The structure of a Burkholderia pseudomallei immunophilin-inhibitor complex reveals new approaches to antimicrobial development. Biochem J, 437, 413-422. PubMed id: 21574961 DOI: 10.1042/BJ20110345
Date:
28-Jan-11     Release date:   25-May-11    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q63J95  (Q63J95_BURPS) -  Peptidyl-prolyl cis-trans isomerase
Seq:
Struc:
113 a.a.
122 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.5.2.1.8  - Peptidylprolyl isomerase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Peptidylproline (omega=180) = peptidylproline (omega=0)
Peptidylproline (omega=180)
= peptidylproline (omega=0)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     protein folding   2 terms 
  Biochemical function     isomerase activity     2 terms  

 

 
    Added reference    
 
 
DOI no: 10.1042/BJ20110345 Biochem J 437:413-422 (2011)
PubMed id: 21574961  
 
 
The structure of a Burkholderia pseudomallei immunophilin-inhibitor complex reveals new approaches to antimicrobial development.
I.H.Norville, K.O'Shea, M.Sarkar-Tyson, S.Zheng, R.W.Titball, G.Varani, N.J.Harmer.
 
  ABSTRACT  
 
No abstract given.