PDBsum entry 2xnx

Cell adhesion

PDB id: 2xnx

Contents

Protein chains

75 a.a.

313 a.a.

303 a.a.

76 a.a.

108 a.a.

PDB id:

2xnx

Name:

Cell adhesion

Title:

Bc1 fragment of streptococcal m1 protein in complex with human fibrinogen

Structure:

Fibrinogen alpha chain. Chain: a, d, g, j. Fragment: fragment d, residues 130-216. Synonym: human fibrinogen. Fibrinogen beta chain. Chain: b, e, h, k. Fragment: fragment d, residues 164-491. Synonym: human fibrinogen. Fibrinogen gamma chain.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Streptococcus pyogenes. Group a streptococcus. Organism_taxid: 1314. Strain: 5448. Expressed in: escherichia coli. Expression_system_taxid: 511693.

Resolution:

3.30Å R-factor: 0.279 R-free: 0.325

Authors:

P.Macheboeuf,C.Y Fu,A.S.Zinkernagel,J.E.Johnson,V.Nizet,P.Ghosh

Key ref:

P.Macheboeuf et al. (2011). Streptococcal M1 protein constructs a pathological host fibrinogen network. Nature, 472, 64-68. PubMed id: 21475196

Date:

06-Aug-10 Release date: 13-Apr-11

Protein chains

P02671  (FIBA_HUMAN) -  Fibrinogen alpha chain from Homo sapiens

Seq: 866 a.a.

Struc: 75 a.a.

Protein chains

P02675  (FIBB_HUMAN) -  Fibrinogen beta chain from Homo sapiens

Seq: 491 a.a.

Struc: 313 a.a.

Protein chains

P02679  (FIBG_HUMAN) -  Fibrinogen gamma chain from Homo sapiens

Seq: 453 a.a.

Struc: 303 a.a.

Protein chain

P02671  (FIBA_HUMAN) -  Fibrinogen alpha chain from Homo sapiens

Seq: 866 a.a.

Struc: 76 a.a.

Protein chains

No UniProt id for this chain

Struc: 108 a.a.

Nature 472:64-68 (2011)

PubMed id: 21475196

Streptococcal M1 protein constructs a pathological host fibrinogen network.

P.Macheboeuf, C.Buffalo, C.Y.Fu, A.S.Zinkernagel, J.N.Cole, J.E.Johnson, V.Nizet, P.Ghosh.

ABSTRACT

No abstract given.