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PDBsum entry 2xms

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protein ligands metals links
Signaling protein PDB id
2xms
Jmol
Contents
Protein chain
281 a.a. *
Ligands
IMD ×2
Metals
_CL
Waters ×137
* Residue conservation analysis
PDB id:
2xms
Name: Signaling protein
Title: Crystal structure of human ndrg2 protein provides insight into its role as a tumor suppressor
Structure: Protein ndrg2. Chain: a. Fragment: alpha-beta hydrolase domain, residues 24-304. Synonym: ndrg2. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Resolution:
2.15Å     R-factor:   0.174     R-free:   0.207
Authors: J.Hwang,Y.Kim,H.Lee,M.H.Kim
Key ref: J.Hwang et al. (2011). Crystal structure of the human N-Myc downstream-regulated gene 2 protein provides insight into its role as a tumor suppressor. J Biol Chem, 286, 12450-12460. PubMed id: 21247902
Date:
29-Jul-10     Release date:   19-Jan-11    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q9UN36  (NDRG2_HUMAN) -  Protein NDRG2
Seq:
Struc:
371 a.a.
281 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 4 residue positions (black crosses)

 

 
J Biol Chem 286:12450-12460 (2011)
PubMed id: 21247902  
 
 
Crystal structure of the human N-Myc downstream-regulated gene 2 protein provides insight into its role as a tumor suppressor.
J.Hwang, Y.Kim, H.B.Kang, L.Jaroszewski, A.M.Deacon, H.Lee, W.C.Choi, K.J.Kim, C.H.Kim, B.S.Kang, J.O.Lee, T.K.Oh, J.W.Kim, I.A.Wilson, M.H.Kim.
 
  ABSTRACT  
 
No abstract given.