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PDBsum entry 2xmr

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protein ligands metals Protein-protein interface(s) links
Signaling protein PDB id
2xmr
Jmol
Contents
Protein chains
281 a.a. *
Ligands
ACT ×3
GOL ×3
Metals
_CA
Waters ×399
* Residue conservation analysis
PDB id:
2xmr
Name: Signaling protein
Title: Crystal structure of human ndrg2 protein provides insight in role as a tumor suppressor
Structure: Protein ndrg2. Chain: a, b, c. Fragment: alpha-beta hydrolase domain, residues 24-304. Synonym: ndrg2. Engineered: yes. Mutation: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Resolution:
2.00Å     R-factor:   0.182     R-free:   0.232
Authors: J.Hwang,Y.Kim,H.Lee,M.H.Kim
Key ref: J.Hwang et al. (2011). Crystal structure of the human N-Myc downstream-regulated gene 2 protein provides insight into its role as a tumor suppressor. J Biol Chem, 286, 12450-12460. PubMed id: 21247902
Date:
29-Jul-10     Release date:   19-Jan-11    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q9UN36  (NDRG2_HUMAN) -  Protein NDRG2
Seq:
Struc:
371 a.a.
281 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 4 residue positions (black crosses)

 

 
J Biol Chem 286:12450-12460 (2011)
PubMed id: 21247902  
 
 
Crystal structure of the human N-Myc downstream-regulated gene 2 protein provides insight into its role as a tumor suppressor.
J.Hwang, Y.Kim, H.B.Kang, L.Jaroszewski, A.M.Deacon, H.Lee, W.C.Choi, K.J.Kim, C.H.Kim, B.S.Kang, J.O.Lee, T.K.Oh, J.W.Kim, I.A.Wilson, M.H.Kim.
 
  ABSTRACT  
 
No abstract given.