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PDBsum entry 2xmn

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protein ligands metals Protein-protein interface(s) links
Transport protein PDB id
2xmn
Jmol
Contents
Protein chains
428 a.a. *
Ligands
LMT
Metals
_CL ×3
Waters ×20
* Residue conservation analysis
PDB id:
2xmn
Name: Transport protein
Title: High resolution snapshots of defined tolc open states presen iris-like movement of periplasmic entrance helices
Structure: Outer membrane protein tolc. Chain: a, b, c. Fragment: residues 23-450. Mutation: yes
Source: Escherichia coli. Organism_taxid: 83333. Strain: k-12. Variant: c41
Resolution:
2.85Å     R-factor:   0.273     R-free:   0.309
Authors: X.Y.Pei,E.Koronakis,C.Hughes,V.Koronakis
Key ref: X.Y.Pei et al. (2011). Structures of sequential open states in a symmetrical opening transition of the TolC exit duct. Proc Natl Acad Sci U S A, 108, 2112-2117. PubMed id: 21245342
Date:
28-Jul-10     Release date:   26-Jan-11    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
P02930  (TOLC_ECOLI) -  Outer membrane protein TolC
Seq:
Struc:
493 a.a.
428 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 3 residue positions (black crosses)

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     membrane   4 terms 
  Biological process     transport   6 terms 
  Biochemical function     transporter activity     4 terms  

 

 
Proc Natl Acad Sci U S A 108:2112-2117 (2011)
PubMed id: 21245342  
 
 
Structures of sequential open states in a symmetrical opening transition of the TolC exit duct.
X.Y.Pei, P.Hinchliffe, M.F.Symmons, E.Koronakis, R.Benz, C.Hughes, V.Koronakis.
 
  ABSTRACT  
 
No abstract given.

 

Literature references that cite this PDB file's key reference

  PubMed id Reference
21513882 E.B.Tikhonova, Y.Yamada, and H.I.Zgurskaya (2011).
Sequential mechanism of assembly of multidrug efflux pump AcrAB-TolC.
  Chem Biol, 18, 454-463.  
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time.

 

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