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PDBsum entry 2xii

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protein ligands Protein-protein interface(s) links
Hydrolase PDB id
2xii
Jmol
Contents
Protein chains
438 a.a. *
Ligands
TYR ×2
TA9 ×2
SO4 ×4
GOL
Waters ×696
* Residue conservation analysis
PDB id:
2xii
Name: Hydrolase
Title: Crystal structure of an alpha-l-fucosidase gh29 from bacteroides thetaiotaomicron in complex with an extended 9- fluorenone iminosugar inhibitor
Structure: Alpha-l-fucosidase. Chain: a, b. Fragment: catalytic domain, 32-484. Synonym: fucosidase, glycoside hydrolase, alpha-l-fucoside fucohydrolase. Engineered: yes
Source: Bacteroides thetaiotaomicron. Organism_taxid: 818. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Resolution:
1.80Å     R-factor:   0.188     R-free:   0.223
Authors: A.Lammerts Van Bueren,S.D.Popat,C.H.Lin,G.J.Davies
Key ref: A.Lammerts van Bueren et al. (2010). Structural and thermodynamic analyses of α-L-fucosidase inhibitors. Chembiochem, 11, 1971-1974. PubMed id: 20665773
Date:
30-Jun-10     Release date:   21-Jul-10    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q8A3I4  (Q8A3I4_BACTN) -  Alpha-L-fucosidase
Seq:
Struc:
484 a.a.
438 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     carbohydrate metabolic process   2 terms 
  Biochemical function     alpha-L-fucosidase activity     1 term  

 

 
Chembiochem 11:1971-1974 (2010)
PubMed id: 20665773  
 
 
Structural and thermodynamic analyses of α-L-fucosidase inhibitors.
A.Lammerts van Bueren, S.D.Popat, C.H.Lin, G.J.Davies.
 
  ABSTRACT  
 
No abstract given.