PDBsum entry 2xfx

Immune system

PDB id: 2xfx

Contents

Protein chains

277 a.a. *

99 a.a. *

11 a.a. *

Waters ×149

* Residue conservation analysis

PDB id:

2xfx

Name:

Immune system

Title:

Cattle mhc class i n01301 presenting an 11mer from theileria parva

Structure:

Mhc class 1. Chain: a. Fragment: residues 22-297. Synonym: n01301. Engineered: yes. Other_details: mhc class i alpha chain. Beta-2-microglobulin. Chain: b. Synonym: lactollin.

Source:

Bos taurus. Cattle. Organism_taxid: 9913. Strain: british friesian cattle. Expressed in: escherichia coli. Expression_system_taxid: 562. Theileria parva. Organism_taxid: 5875

Resolution:

1.90Å R-factor: 0.200 R-free: 0.238

Authors:

I.K.Macdonald,M.Harkiolaki,L.Hunt,W.I.Morrison,T.Connelley, S.P.Graham,E.Y.Jones,D.R.Flower,S.A.Ellis

Key ref:

I.K.Macdonald et al. (2010). MHC class I bound to an immunodominant Theileria parva epitope demonstrates unconventional presentation to T cell receptors. Plos Pathog, 6, e1001149. PubMed id: 20976198

Date:

28-May-10 Release date: 27-Oct-10

Protein chain

Q30291  (Q30291_BOVIN) -  MHC class 1 from Bos taurus

Seq: 358 a.a.

Struc: 277 a.a.*

Protein chain

P01888  (B2MG_BOVIN) -  Beta-2-microglobulin from Bos taurus

Seq: 118 a.a.

Struc: 99 a.a.

Protein chain

Q4MYJ2  (Q4MYJ2_THEPA) -  Uncharacterized protein from Theileria parva

Seq: 543 a.a.

Struc: 11 a.a.

* PDB and UniProt seqs differ at 1 residue position (black cross)

Plos Pathog 6:e1001149 (2010)

PubMed id: 20976198

MHC class I bound to an immunodominant Theileria parva epitope demonstrates unconventional presentation to T cell receptors.

I.K.Macdonald, M.Harkiolaki, L.Hunt, T.Connelley, A.V.Carroll, N.D.MacHugh, S.P.Graham, E.Y.Jones, W.I.Morrison, D.R.Flower, S.A.Ellis.

ABSTRACT

No abstract given.