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PDBsum entry 2x8l

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protein ligands links
Oxidoreductase PDB id
2x8l
Jmol
Contents
Protein chain
311 a.a. *
Ligands
GOL
Waters ×318
* Residue conservation analysis
PDB id:
2x8l
Name: Oxidoreductase
Title: Plasmodium falciparum lactate dehydrogenase apo structure
Structure: L-lactate dehydrogenase. Chain: a. Synonym: ldh-p. Engineered: yes
Source: Plasmodium falciparum. Organism_taxid: 5833. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: malaria parasite
Resolution:
1.60Å     R-factor:   0.137     R-free:   0.167
Authors: R.W.Birkinshaw,R.L.Brady
Key ref: R.W.Birkinshaw and r.l.brady The apo crystal structure of plasmodium falciparum la dehydrogenase. To be published, .
Date:
10-Mar-10     Release date:   23-Mar-10    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q71T02  (Q71T02_PLAFA) -  L-lactate dehydrogenase
Seq:
Struc:
316 a.a.
311 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.1.1.1.27  - L-lactate dehydrogenase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: (S)-lactate + NAD+ = pyruvate + NADH
(S)-lactate
Bound ligand (Het Group name = GOL)
matches with 71.43% similarity
+ NAD(+)
= pyruvate
+ NADH
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     oxidation-reduction process   3 terms 
  Biochemical function     catalytic activity     4 terms