spacer
spacer

PDBsum entry 2x83

Go to PDB code: 
protein Protein-protein interface(s) links
Viral protein PDB id
2x83
Jmol
Contents
Protein chains
146 a.a.
163 a.a. *
Waters ×634
* Residue conservation analysis
PDB id:
2x83
Name: Viral protein
Title: Evolutionary basis of HIV restriction by the antiretroviral
Structure: HIV-1 capsid. Chain: a, c. Fragment: n-terminal domain, residues 401-564. Engineered: yes. Trimcyp. Chain: b, d. Fragment: residues 304-466
Source: Human immunodeficiency virus type 1. HIV-1. Organism_taxid: 82834. Strain: lw12.3 isolate. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Macaca. Organism_taxid: 9539
Resolution:
1.70Å     R-factor:   0.163     R-free:   0.246
Authors: A.J.Price,L.C.James
Key ref: L.M.Ylinen et al. (2010). Conformational adaptation of Asian macaque TRIMCyp directs lineage specific antiviral activity. PLoS Pathog, 6, e1001062. PubMed id: 20808866
Date:
05-Mar-10     Release date:   15-Sep-10    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
No UniProt id for this chain
Struc: 146 a.a.
Protein chains
Pfam   ArchSchema ?
B0ZE32  (B0ZE32_MACFA) -  TRIM5/CypA fusion protein (Fragment)
Seq:
Struc:
467 a.a.
163 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     viral reproduction   3 terms 
  Biochemical function     peptidyl-prolyl cis-trans isomerase activity     1 term  

 

 
PLoS Pathog 6:e1001062 (2010)
PubMed id: 20808866  
 
 
Conformational adaptation of Asian macaque TRIMCyp directs lineage specific antiviral activity.
L.M.Ylinen, A.J.Price, J.Rasaiyaah, S.Hué, N.J.Rose, F.Marzetta, L.C.James, G.J.Towers.
 
  ABSTRACT  
 
No abstract given.