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PDBsum entry 2x0m

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Isomerase PDB id
2x0m
Jmol
Contents
Protein chains
233 a.a.
Ligands
3PG
Waters ×532
Superseded by: 2x2g
PDB id:
2x0m
Name: Isomerase
Title: Crystallographic binding studies with an engineered monomeric variant of triosephosphate isomerase
Structure: Triosephosphate isomerase, glycosomal. Chain: a, b. Fragment: residues 2-13,15-72,80-234,238-250. Synonym: tim, triose-phosphate isomerase. Engineered: yes. Mutation: yes. Other_details: a monomeric mutant of trypanosomal triosephosphate isomerase, which has a bound 3pga molecule in an active site
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Resolution:
1.91Å     R-factor:   0.170     R-free:   0.224
Authors: M.Salin,E.G.Kapetaniou,M.Vaismaa,M.Lajunen,M.G.Castejeijn, P.Neubauer,L.Salmon,R.Wierenga
Key ref: M.Salin et al. Crystallographic binding studies with an engineered monomeric variant of triosephosphate isomerase. To be published, .
Date:
16-Dec-09     Release date:   29-Dec-09    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
P04789  (TPIS_TRYBB) -  Triosephosphate isomerase, glycosomal
Seq:
Struc:
250 a.a.
233 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 10 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: E.C.5.3.1.1  - Triose-phosphate isomerase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: D-glyceraldehyde 3-phosphate = glycerone phosphate
D-glyceraldehyde 3-phosphate
= glycerone phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site