PDBsum entry: 2wii

Immune system

PDB id: 2wii

Contents

Protein chains

640 a.a. *

896 a.a. *

245 a.a. *

Ligands

GOL ×17

NAG-NAG-BMA-BMA-BMA-BMA

NAG

Metals

_CA

Waters ×172

* Residue conservation analysis

PDB id:

2wii

Name:

Immune system

Title:

Complement c3b in complex with factor h domains 1-4

Structure:

Complement c3 beta chain. Chain: a. Fragment: residues 23-667. Synonym: complement c3, c3 and pzp-like alpha-2- macroglobulin domain-containing protein 1. Complement c3b alpha' chain. Chain: b. Fragment: residues 749-1663. Synonym: complement c3, c3 and pzp-like alpha-2-

Source:

Homo sapiens. Human. Organism_taxid: 9606. Expressed in: homo sapiens. Expression_system_taxid: 9606.

Resolution:

2.70Å R-factor: 0.218 R-free: 0.251

Authors:

J.Wu,B.J.C.Janssen,P.Gros

Date:

12-May-09 Release date: 09-Jun-09

Protein chain

P01024  (CO3_HUMAN) -  Complement C3

Seq: 1663 a.a.

Struc: 640 a.a.

Protein chain

P01024  (CO3_HUMAN) -  Complement C3

Seq: 1663 a.a.

Struc: 896 a.a.

Protein chain

P08603  (CFAH_HUMAN) -  Complement factor H

Seq: 1231 a.a.

Struc: 245 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

 Gene Ontology (GO) functional annotation 

• Cellular component: extracellular region (2 terms)
• Biochemical function: protein binding (2 terms)