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Contents |
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* Residue conservation analysis
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PDB id:
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Transferase
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Title:
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Structure of c-terminal actin depolymerizing factor homology (adf-h) domain of human twinfilin-2
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Structure:
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Twinfilin-2. Chain: a. Fragment: actin depolymerizing factor homology (adf-h) doma residues 181-313. Synonym: twinfilin-1-like protein, a6-related protein, prot tyrosine kinase 9-like. Engineered: yes. Mutation: yes. Other_details: y309d is a cloning artefact
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: r3-prare2.
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Resolution:
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1.80Å
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R-factor:
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0.189
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R-free:
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0.236
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Authors:
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J.M.Elkins,A.C.W.Pike,E.Salah,P.Savitsky,J.W.Murray,A.Roos, F.Von Delft,A.Edwards,C.H.Arrowsmith,M.Wikstrom,C.Bountra,S
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Key ref:
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J.M.Elkins
et al.
Structure of c-Terminal actin depolymerizing factor homology (adf-H) domain of human twinfilin- 2.
To be published,
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Date:
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18-Aug-08
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Release date:
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30-Sep-08
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PROCHECK
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Headers
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References
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Q6IBS0
(TWF2_HUMAN) -
Twinfilin-2
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Seq:
Struc:
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349 a.a.
135 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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*
PDB and UniProt seqs differ
at 3 residue positions (black
crosses)
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Gene Ontology (GO) functional annotation
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Cellular component
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intracellular
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1 term
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Biochemical function
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actin binding
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1 term
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Links
