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PDBsum entry 2vw1

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protein ligands links
Hydrolase PDB id
2vw1
Jmol
Contents
Protein chain
658 a.a. *
Ligands
DAN
GOL
Waters ×463
* Residue conservation analysis
PDB id:
2vw1
Name: Hydrolase
Title: Crystal structure of the nanb sialidase from streptococcus pneumoniae
Structure: Sialidase b. Chain: a. Synonym: nanb sialidase, neuraminidase b. Engineered: yes
Source: Streptococcus pneumoniae. Organism_taxid: 1313. Strain: tigr. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Resolution:
2.39Å     R-factor:   0.196     R-free:   0.278
Authors: G.Xu,J.A.Potter,R.J.M.Russell,M.R.Oggioni,P.W.Andrew, G.L.Taylor
Date:
13-Jun-08     Release date:   24-Jun-08    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q54727  (NANB_STRPN) -  Sialidase B
Seq:
Struc:
 
Seq:
Struc:
697 a.a.
658 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.3.2.1.18  - Exo-alpha-sialidase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     carbohydrate metabolic process   1 term 
  Biochemical function     exo-alpha-sialidase activity     1 term