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PDBsum entry 2vsw

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protein Protein-protein interface(s) links
Hydrolase PDB id
2vsw
Jmol
Contents
Protein chain
134 a.a. *
Waters ×91
* Residue conservation analysis
PDB id:
2vsw
Name: Hydrolase
Title: The structure of the rhodanese domain of the human dual specificity phosphatase 16
Structure: Dual specificity protein phosphatase 16. Chain: a, b. Fragment: rhodanese domain, residues 5-150. Synonym: mitogen-activated protein kinase phosphatase 7, ma phosphatase 7, mkp-7, dusp16. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Resolution:
2.20Å     R-factor:   0.172     R-free:   0.227
Authors: J.W.Murray,A.Barr,A.C.W.Pike,J.Elkins,C.Phillips,J.Wang,P.Sa A.Roos,S.Bishop,M.Wickstroem,C.Bountra,A.M.Edwards,C.H.Arro N.Burgess-Brown,N.Pantic,J.Bray,F.Von Delft,O.Gileadi,S.Kna
Key ref: J.W.Murray et al. The structure of the rhodanese domain of the human dual specifity phosphatase 16. To be published, .
Date:
30-Apr-08     Release date:   15-Jul-08    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q9BY84  (DUS16_HUMAN) -  Dual specificity protein phosphatase 16
Seq:
Struc:
 
Seq:
Struc:
665 a.a.
134 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class 2: E.C.3.1.3.16  - Protein-serine/threonine phosphatase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: [a protein]-serine/threonine phosphate + H2O = [a protein]- serine/threonine + phosphate
[a protein]-serine/threonine phosphate
+ H(2)O
= [a protein]- serine/threonine
+ phosphate
   Enzyme class 3: E.C.3.1.3.48  - Protein-tyrosine-phosphatase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Protein tyrosine phosphate + H2O = protein tyrosine + phosphate
Protein tyrosine phosphate
+ H(2)O
= protein tyrosine
+ phosphate
Note, where more than one E.C. class is given (as above), each may correspond to a different protein domain or, in the case of polyprotein precursors, to a different mature protein.
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     protein dephosphorylation   1 term 
  Biochemical function     MAP kinase tyrosine/serine/threonine phosphatase activity     1 term