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Hydrolase/translation PDB id
2vso
Jmol
Contents
Protein chains
366 a.a. *
239 a.a. *
Ligands
AMP ×2
Waters ×76
* Residue conservation analysis
PDB id:
2vso
Name: Hydrolase/translation
Title: Crystal structure of a translation initiation complex
Structure: Atp-dependent RNA helicase eif4a. Chain: a, b. Synonym: eukaryotic initiation factor 4a, eif-4a, translation initiation factor 1/2, stimulator factor i 37 kda component, p37, eif4a. Engineered: yes. Eukaryotic initiation factor 4f subunit p150. Chain: e, f. Fragment: middle domain, 4a-binding, 572-854.
Source: Saccharomyces cerevisiae. Organism_taxid: 4932. Atcc: 96604. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_variant: rosetta. Expression_system_taxid: 469008.
Resolution:
2.60Å     R-factor:   0.215     R-free:   0.260
Authors: P.Schutz,M.Bumann,A.E.Oberholzer,C.Bieniossek,M.Altmann, H.Trachsel,U.Baumann
Date:
28-Apr-08     Release date:   24-Jun-08    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
P10081  (IF4A_YEAST) -  ATP-dependent RNA helicase eIF4A
Seq:
Struc: 		395 a.a.
366 a.a.
Protein chains
Pfam   ArchSchema ?
P39935  (IF4F1_YEAST) -  Eukaryotic initiation factor 4F subunit p150
Seq:
Struc: 		 
Seq:
Struc: 		952 a.a.
239 a.a.
Key:    PfamA domain  PfamB domain  Secondary structure

 Enzyme reactions 
   Enzyme class: Chains A, B: E.C.3.6.4.13  - Rna helicase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: ATP + H2O = ADP + phosphate
ATP
 + H(2)O
 =
ADP
Bound ligand (Het Group name = AMP)
matches with 85.00% similarity 		+ phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cytoplasm   4 terms 
  Biological process     RNA metabolic process   3 terms 
  Biochemical function     binding     11 terms