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PDBsum entry 2vr2

Go to PDB code: 
protein metals links
Hydrolase PDB id
2vr2
Jmol
Contents
Protein chain
478 a.a. *
Metals
_CL
_ZN ×2
Waters ×1
* Residue conservation analysis
PDB id:
2vr2
Name: Hydrolase
Title: Human dihydropyrimidinase
Structure: Dihydropyrimidinase. Chain: a. Synonym: dhpase, dhp, dihydropyrimidine amidohydrolase, hydantoinase. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Resolution:
2.80Å     R-factor:   0.203     R-free:   0.251
Authors: M.Welin,T.Karlberg,J.Andersson,C.H.Arrowsmith,H.Berglund,R.D R.Collins,L.G.Dahlgren,A.M.Edwards,S.Flodin,A.Flores,S.Gras M.Hammarstrom,M.D.Herman,I.Johansson,A.Kallas,T.Kotenyova,L M.Moche,M.E.Nilsson,T.Nyman,C.Persson,J.Sagemark,L.Svensson A.G.Thorsell,L.Tresaugues,S.Van Den Berg,J.Weigelt,M.Wikstr P.Nordlund,Structural Genomics Consortium
Key ref: M.Welin et al. The crystal structure of human dihydropyrimidinase. To be published, .
Date:
25-Mar-08     Release date:   01-Apr-08    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q14117  (DPYS_HUMAN) -  Dihydropyrimidinase
Seq:
Struc:
519 a.a.
478 a.a.
Key:    PfamA domain  PfamB domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.3.5.2.2  - Dihydropyrimidinase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: 5,6-dihydrouracil + H2O = 3-ureidopropanoate
5,6-dihydrouracil
+ H(2)O
= 3-ureidopropanoate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cytoplasm   3 terms 
  Biological process     small molecule metabolic process   11 terms 
  Biochemical function     hydrolase activity     10 terms