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PDBsum entry 2vph

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protein Protein-protein interface(s) links
Hydrolase PDB id
2vph
Jmol
Contents
Protein chains
98 a.a. *
92 a.a. *
Waters ×72
* Residue conservation analysis
PDB id:
2vph
Name: Hydrolase
Title: Crystal structure of the human protein tyrosine phosphatase, non-receptor type 4, pdz domain
Structure: Tyrosine-protein phosphatase non-receptor type 4. Chain: a, b. Fragment: pdz domain, residues 513-606. Synonym: protein-tyrosine phosphatase meg1, ptpase-meg1, me engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: r3-rosetta-prare2.
Resolution:
1.90Å     R-factor:   0.210     R-free:   0.243
Authors: A.K.Roos,J.Wang,N.Burgess-Brown,J.M.Elkins,K.Kavanagh,A.C.W. P.Filippakopoulos,C.H.Arrowsmith,J.Weigelt,A.Edwards,F.Von C.Bountra,S.Knapp
Key ref: A.K.Roos et al. Crystal structure of the human protein tyrosine phosphatase, Non-Receptor type 4, Pdz domain. To be published, .
Date:
29-Feb-08     Release date:   18-Mar-08    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P29074  (PTN4_HUMAN) -  Tyrosine-protein phosphatase non-receptor type 4
Seq:
Struc:
 
Seq:
Struc:
926 a.a.
98 a.a.*
Protein chain
Pfam   ArchSchema ?
P29074  (PTN4_HUMAN) -  Tyrosine-protein phosphatase non-receptor type 4
Seq:
Struc:
 
Seq:
Struc:
926 a.a.
92 a.a.*
Key:    PfamA domain  PfamB domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 7 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: Chains A, B: E.C.3.1.3.48  - Protein-tyrosine-phosphatase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Protein tyrosine phosphate + H2O = protein tyrosine + phosphate
Protein tyrosine phosphate
+ H(2)O
= protein tyrosine
+ phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site