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Oxidoreductase
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PDB id
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2vd7
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Contents |
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* Residue conservation analysis
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PDB id:
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Oxidoreductase
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Title:
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Crystal structure of jmjd2a complexed with inhibitor pyridine-2,4-dicarboxylic acid
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Structure:
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Jmjc domain-containing histone demethylation prot chain: a, b. Fragment: catalytic domain, residues 1-359. Synonym: jumonji domain-containing protein 2a. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Expressed in: eschericia coli. Expression_system_taxid: 562.
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Resolution:
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2.25Å
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R-factor:
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0.172
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R-free:
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0.219
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Authors:
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S.S.Ng,F.Von Delft,E.S.Pilka,K.L.Kavanagh,M.A.Mcdonough,P.Sa C.H.Arrowsmith,J.Weigelt,A.Edwards,M.Sundstrom,C.J.Schofiel U.Oppermann
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Key ref:
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S.S.Ng
et al.
Crystal structure of jmjd2a complexed with inhibitor pyridine-2,4-Dicarboxylic acid.
To be published,
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Date:
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01-Oct-07
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Release date:
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27-Nov-07
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PROCHECK
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Headers
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References
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O75164
(KDM4A_HUMAN) -
Lysine-specific demethylase 4A
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Seq:
Struc:
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1064 a.a.
350 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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Gene Ontology (GO) functional annotation
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Biochemical function
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protein binding
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1 term
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Links
